2,6-DIAROYL-3,5-DIARYL-4-METHYLTETRAHYDRO-1,4-THIAZINE-1,1-DIOXIDES - A SYNTHETIC AND STEREOCHEMICAL STUDY

Abstract Conjugate addition of methy lamine over 2,2′-sulfonylbis(1.3-diarylprop-2-en-1-ones) in dimethylformamide gave the hitherto unknown 2.6-diaroyl-3,5-diaryl-4-methyltetrahydro- 1.4-thiazine-1,1-dioxides in very good yields. The same thiazines were also obtained by condensation of bis(aroylmethyl)sulfones with aromatic aldehydes and methylamine. The structure and stereochemistry of the compounds were deduced from elemental analysis and spectral data.