Characteristics of hemoglycolysis in patients with chronic ischemic heart disease complicated by circulatory insufficiency

Alterations in the patterns of hemoglycolysis (ATP, 2,3-diphosphoglycerate, glucose, lactate, pyruvate) were studied after incubation of erythrocytes from 98 patients with chronic ischemic heart disease and 27 practically healthy persons. The incubation of erythrocytes within 2 hrs enabled to detect the typical impairments in regulation of glycolysis occurring in erythrocytes of the patients as well as to find two main types of its alteration, corresponding to clinical manifestations in the circulation insufficiency.