THE ACUTE-PHASE AND HEMOSTATIC RESPONSE IN DROMEDARY CAMELS (CAMELUS DROMEDARIUS)

Abstract:  Acute-phase reactants indicate inflammation and are increasingly used in veterinary medicine to indicate and to monitor progression of disease. Hemostasis and inflammation have interconnected pathophysiologic pathways and influence each other on different levels. This study established observed normal ranges for acute-phase reactants and for coagulation and thromboelastographic (TEG) parameters in 49 dromedary camels (Camelus dromedarius) and assessed the response to chronic and acute inflammation. Chronically infected animals suffering from lymph abscessation due to Corynebacterium spp. had significantly higher concentrations of the acute-phase reactants haptoglobin (P < 0.005) and fibrinogen (P < 0.013) and an increased clot strength characterized by an increase of the TEG parameters MA (P < 0.039), representing the maximum amplitude of the clot strengths, and G, the global clot strength (P < 0.022), compared to healthy animals. When the acute-phase and hemostatic responses of 10 males receiv...