CLOFILIUM, A POTENT BLOCKER OF SODIUM AND CALCIUM CHANNELS IN GUINEA-PIG VENTRICULAR MYOCYTES

The unsatisfactory results of clinical trials with class-Ⅰ antiarrhythmic drugs have prompted a renaissance of interest in compounds with class-Ⅲ antiarrhythmic action. In the present, we have reevaluated the class-Ⅲ antiarrhythmic ef-