Comparative Analysis of a Retrospective Vs Prospective Study Ascertaining Spectrum of Renal Lesions: Experience of a Tertiary Care Teaching Centre in North India

The present study was undertaken over a period of thirteen years in two halves: 10 years retrospective and 3 years prospective at a single tertiary care centre in the northern part of India, so as to take make a comparison in the same area over a time period and also to over all take a glimpse into the pattern of the disease. Ten year retrospective data in this study showed that glomerulonephritis (57.55%) were the most common of the 172 renal lesions followed by chronic pyelonephritis on nephrectomy specimen (20.93%). Membranous glomerulonephritis (MG) was commonest glomerulopathy, accounting for 14.14% of all glomerulopathies. In the prospective study glomerulonephritis (78.39%) was the most common lesion. Similar to retrospective study, CPN on nephrectomy followed the glomerulopathies as the next most common renal lesion (10.55%). End stage renal disease (ESRD) was however the most common glomerulonephritis in the prospective study. The study thus concludes that ESRD along with CPN (both leading to dialysis dependant renal failure) continues be the major challenge to patients suffering from renal disorders. The incidence of dialysis dependant kidney has increased over the years.