Rhodamine dyes soluble in water and containing conjugates.

2000 
rhodamine dyes and their salts with the formula ** ** in which R9 is an ortho, carboxy or sulfophenyl of the formula I wherein: n is 1, 2 or 3; Y is the xanthene ring system Y-1 Original rhodamine; R1 is selected from the group consisting of hydrogen and (C1-C6) alkyl; R2 when taken alone, is selected from the group consisting of hydrogen and (C1-C6) alkyl or, when taken together with R3 and R3? is (C2-C6) alquilodiilo or (C2-C6) alkylene; R3, when taken alone, is selected from the group consisting of hydrogen, (C1-C6) alkyl, (C5-C14) aryl and (C5-C14) arylaryl, or when taken together R3? is (C4-C6 ) alquilodiilo or (C4-C6) alkylene, or when taken individually with R2 or R4 is (C2-C6) alquilodiilo or (C2- C6) alkylene; and wherein the ring system Y-1 optionally includes one or more binding structures selected from the group consisting of an azide group, a monosubstituted primary amine, a secondary amine disubstituted, a thiol, a hydroxyl, unhalogeno, epoxide, N- hidroxisuccinimidiilo ester, a carboxyl and an activated ester and is connected to a connecting structure -L- a xanthene nitrogen atom or the 4-position of Y-1 or group Z.
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