CML with an e1a3 BCR-ABL fusion: rare, benign, and a potential diagnostic pitfall.

Most patients with BCR-ABL –positive chronic myeloid leukemia (CML) express e13a2 (b2a2) or e14a2 (b3a2) mRNAs that result from a rearrangement of the major breakpoint cluster region (M- BCR ), while rearrangements of the minor BCR with e1a2 transcripts are rare in CML.[1][1]Variation of the