In-vivo and in-vitro interference of antibiotics with antigen-specific antibody responses: effect of josamycin

The effects of josamycin on the antigen-specific primary antibody responses of human peripheral blood cells have been studied by the method of haemolytic colonies in soft agar. The tests were performed before and after the oral administration of 1 g of josamycin of by adding the drug directly to cultures of cells from untreated donors