Population pharmacokinetics of single-dose amikacin in critically ill patients with suspected ventilator-associated pneumonia
2015
Aims
Modifications of antimicrobials’ pharmacokinetic parameters have been reported in critically ill patients, resulting in a risk of treatment failure. We characterized amikacin pharmacokinetic variability in critically ill patients with ventilator-associated pneumonia (VAP) and evaluated several dosing regimens.
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