Crystal structure, thermal decomposition kinetics and antimicrobial activities of [Zn(eatz)2(OAc)2] (eatz = 5-ethyl-2-amino-1,3,4-thiadiazole)

Abstract The synthesis and characterization of a Zn(II) complex with 5-ethyl-2-amino-1,3,4-thiadiazole (eatz) are described. The crystal structure of [Zn(eatz) 2 (OAc) 2 ] was determined by X-ray diffraction. The crystal belongs to the monoclinic system and the structural unit is a distorted tetrahedron. In this complex, eatz acts as a monodentate ligand coordinating through the thiadiazole N atom to Zn(II), and the crystal structure is mainly stabilized by both intra- and intermolecular hydrogen bonds. Thermal analysis reveals that the complex [Zn(eatz) 2 (OAc) 2 ] decomposes in three transitions to give Zn(CN) 2 as the end product at 650 °C in N 2 atmosphere. The thermal decomposition kinetic analysis of the title complex indicates that the first transition is a double-step reaction with the main reaction being an n th auto-catalysis one. A biological activity study shows that both the ligand and the complex have good antimicrobial activities against Staphylococcus aureus .