Von Recklinghausen’s Disease with Diabetes Mellitus

THIS CASE is reported because of the unusual finding of diabetes mellitus with Von Reck linghausen’s disease. A survey of the literature has failed to find mention of these two conditions associated in one individual. Fairly complete reviews of Von Recklinghausen’s disease are available (1-7). The term, Von Recklinhausen’s disease, is preferred to neurofibromatosis by many authors. This seems justifiable because the condition appears to be a complex syndrome which may manifest itself in one or more different forms. It is unfortunate that the term, Von Recklinghausen’s disease, is also applied to osteitis fibrosa cystica. Makism (5) lists the following forms in which the disease may make itself evident: (a) formes frustes (incomplete) showing cafe au lait spots, (b) multiple neurofibromatosis (cutaneous, sub cutaneous, peripheral nerve, cranial nerve, spinal nerve or sympathetic nerve tumors), (c) neurofibroma tosis with osseous changes, (d) elephantiasis neuro matosa, (e) mental changes and (f) endocrine ...