Characteristic Manifestations and Accessory Examination of Neuropsychiatric Systemic Lupus Erythematosus

Objective To investigate the characteristic manifestations and accessory examination of neuropsychiatric systemic lupus erythematosus(NPSLE) in clinical practice.Methods A total of 84 NPSLE patients were included.Their clinical manifestations and the results of accessory examinations such as serology,cerebra spinal fluid(CSF),head magnetic resonance imaging(MRI) and computer tomography(CT) were retrospectively analyzed.Results There were 14 NPSLE symptoms found in these patients and the most frequent manifestations of the NPSLE included headache,psychiatric disorder,seizure,and stroke;45% patients existed more than two syndromes.The 44 patients received MRI or CT evaluation and 38 showed abnormal.Conclusion Diagnosis of NPSLE is mainly based on its multiform clinical manifestations,and head MRI and CT examination may be helpful.More specific evaluation requires further development.