Transdermal pasted agents for administering fentanyl
2002
PROBLEM TO BE SOLVED: To provide a method for transdermal administration of fentanyl and an analog thereof for analgesia, and a patch therefor.SOLUTION: The present invention relates to a transdermal patch for administering fentanyl or an analog thereof through the skin comprising: a backing layer; and a reservoir disposed on the backing layer, wherein the reservoir has a thickness of about 0.0125-0.1 mm, at least the skin contacting surface of the reservoir is adhesive, and the reservoir comprises a single phase polymeric composition free of undissolved components containing an amount of fentanyl or an analog thereof sufficient to induce and maintain analgesia in a human for at least three days. And the patch is a rate controlling-free monolithic transdermal patch, wherein fentanyl of a base form is present in the amount of about 7-12% by weight.SELECTED DRAWING: None
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