Particle overload in the rat lung and lung cancer : implications for human risk assessment : proceedings of a conference held at the Massachusetts Institute of Technology on March 29 and 30, 1995

Lung overload - the dilemma and opportunities for resolution from the lab bench to the workplace - implications of toxicology studies on occupational medical practice epidemiological studies in North American carbon black workers comparativeresponse to long-term particle exposure among rats, mice and hamsters significance of particle parameters in the evaluation of exposure-dose-response relationships of inhaled particles current information on lung overload in non-rodent mammals maximumtolerated dose in particulate inhalation studies - a pathologist's point of view differences between rodents and humans in lung tumor response - lessons from recent studies with carbon black role of inflammation in the development of rat lung tumors inresponse to chronic particle exposure evalution of the carcinogenic risk of biochemically inert insoluble particles by the EPA using rat inhalation data use of hazard and risk information in risk management decisions - solid particles and fibres underEPA's TSUSAU and EPCRA lung cancer in rats from prolonged exposure to high concentrates of particles - implications for human risk assessment.