The possible proton translocating activity of the mitochondrial uncoupling protein of brown adipose tissue: Reconstitution studies in liposomes
1983
Abstract Loose coupling of thermogenic mitochondira of brown adipose tissue is related to a high proton (or hydroxyl) conductance of the inner membrane and to the presence of a unique 32 kDa uncoupling protein. Reconstitution experiments of the purified protein in liposomes are reported which suggest that this component could form proton channels in the membrane.
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