Магнитно-резонансная томография в диагностике позднего рассеянного склероза

Purpose: the analysis of morphological changes in the brain in late-onset multiple sclerosis (MS), the assessment of their effect on the degree of neurological deficit. The MR-picture of the brain and the upper cervical spine in patients with clinically isolated syndrome and the onset of multiple sclerosis after 50 years of age has been studied. The dissociation between clinical and pathomorphological signs at the primary examination of patients was found. The most common localization of the demyelinization foci in the brain is described. The gradual increase in the number of foci in the brain as well as the increase in the total amount of demyelinization by 31.7% within the 5-year’s period was marked. The correlation between neurological deficit, foci localization and total amount of demyelinization was not found.