Magnetic Resonance Imaging/Transrectal Ultrasound Fusion-Guided Biopsy of the Prostate to Detect High-Grade Cancer

Abstract Introduction: Multiparametric magnetic resonance imaging (MRI) has been shown to be a valuable adjunct to identifying suspicious lesions for prostate cancer diagnosis.1 MRI/transrectal ultrasound (MRI/TRUS) fusion platforms allow for the detail and information provided by MRI to be combined with the real-time capabilities of ultrasound in an office-based setting. Additionally, MRI/TRUS fusion platforms have demonstrated improved detection of clinically significant prostate cancer compared to standard of care systematic 12-core transrectal ultrasound biopsies.2 Materials and Methods: This video demonstrates the MRI/TRUS fusion biopsy procedure of a 62-year-old male with a history of elevated serum prostate specific antigen (PSA) in the setting of multiple negative TRUS biopsies. The patient was initially biopsied under the standard of care 12-core TRUS with no evidence of prostate cancer with subsequent TRUS biopsies also demonstrating no evidence of cancer. The patient then elected to undergo MRI...