Abstract 734: Altered Loading of Protein Cargoes in Tissue-Entrapped Human Vascular and Valvular Extracellular Vesicles

Mark C. Blaser,Fabrizio Buffolo,Hideyuki Higashi,Maximillian A. Rogers,Lang H. Lee,Tan Pham,Eugenia Shvartz,Galina K. Sukhova,Silvia Monticone,Giovanni Camussi,Jochen D. Muehlschlegel,Simon C. Body,Peter Libby,Sasha A. Singh,Masanori Aikawa,Elena Aikawa

Abstract 734: Altered Loading of Protein Cargoes in Tissue-Entrapped Human Vascular and Valvular Extracellular Vesicles

2019

Mark C. Blaser
Fabrizio Buffolo
Hideyuki Higashi
Maximillian A. Rogers
Lang H. Lee
Tan Pham
Eugenia Shvartz
Galina K. Sukhova
Silvia Monticone
Giovanni Camussi
Jochen D. Muehlschlegel
Simon C. Body
Peter Libby
Sasha A. Singh
Masanori Aikawa
Elena Aikawa

Less than half of all patients develop both vascular and valvular calcification, suggesting differential drivers of disease. Extracellular vesicles (EVs) carry bioactive cargoes that can mediate in...

Keywords:

valvular calcification
Pathology
extracellular vesicles
Chemistry
Calcification
Aortic valve stenosis

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