McCune-Albright-Syndrom in Assoziation mit Meningeom sowie mentaler und psychischer Retardierung

: Report of a boy aged 17 years and review of the literature on the neoplasias of CAS. The cause of examination was a psychic maldevelopment. Cranial arteriography exhibited extreme wide Carotis communis and CT temporal meningioma right and septum pellucidum cyste. A psychic frontal lobe syndrome and cosmetic impairment by skull changes of the CAS are discussed being partial causes of the psychic maldevelopment. Atypical there were retardation of calcification and dentition, bilateral coarctation of the auditory passage with resulting hearing loss. Till now only J. Frankel and coworkers have published the case of a 50 year old Pakistani with the combination of CAS and Meningioma as a complication of fibrous dysplasia of the skull. We suppose relations between CAS and neurofibromatosis and its blastomatous tendency to meningioma.