Antibacterial and Solubility Analysis of Experimental Phytotherapeutic Paste for Endodontic Treatment of Primary Teeth

Objective:  To evaluate the antibacterial effect and the solubility of experimental root canal filling pastes containing the phytoconstituents terpineol and cinnamaldehyde.  Material and Methods: Minimum Inhibitory Concentration (MIC) of each phytoconstituent was determined against  Enterococcus faecalis . Five groups of antibiotic pastes based on zinc oxide were obtained by mixing: only terpineol, only cinnamaldehyde, terpineol and cinnamaldehyde combined, chlorhexidine (antibiotic control), and CTZ paste (control paste). Antibacterial activity was analyzed through direct contact test within 24 and 72 hours. Solubility was evaluated by spectrophotometry within 48 and 144 hours. Antibacterial activity data were analyzed descriptively, and solubility data was analyzed using ANOVA and Tukey tests (p 0.05). After and 144h, highest solubility was observed in the terpineol paste (p 0.05) .  Conclusion:  Pastes containing cinnamaldehyde or terpineol+cinnamaldehyde showed antibacterial activity against  E. faecalis  similar to CTZ paste, with lower solubility.