Ionization methods, mass spectrometry, extraction and purification methods

Object of the present invention is that when the material is ionized by a minute amount in the atmosphere is easier to achieve soft ionization. Ionization method is contained in the liquid substance is used, the ionization method is characterized by comprising: supplying the liquid from the probe to the substrate and with which the substance is dissolved in the liquid forms a liquid bridge between the detector and the substrate ; step oscillating said probe; ion extraction field is generated between the probe electrode and the conductive portion in contact with the liquid.