A Convenient Synthesis of N,N-Dimethylformamidines from Sulfonamides
2015
N , N -Dimethylformamidines were synthesized from sulfonamides using the Vilsmeier reagent as a cleavage activator. The reactions were performed under mild conditions achieving good to excellent yields. The chemistry presented can also be used as a deprotection strategy when amines or anilines are protected with sulfonyl groups, such as the tosyl group.
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