Epidemiologic and Immunologic Considerations on the Pathogenesis of Burkitt's Tumor

Burkitt’s Tumor (BT) is identified as a malignant lymphoma composed predominantly of lymphoid cells similar to those found in the germinal centers of lymphoreticular tissues under normal conditions of antigenic stimulation [1, 2, 3]. The normal cell that morphologically most closely resembles the Burkitt tumor cell is the germinoblast of LENNERT [3, 4], and there may be only slight quantitative differences to a cell called immunoblast by DAMASHEK [5] (Figs. 1–3).