Preferential localization of hafnium in nodular lymphatic cells. Study by electron microprobe

: In a previous work we used the electron microprobe to study the intracellular localization of zirconium after administration of soluble salt at low doses. That element was concentrated in nodular lymphatic cells. In the present work using the same methods we studied hafnium, another element in group IVb of the periodic table, which has chemical properties similar to zirconium. After administration at low doses of soluble salt of hafnium, this element was similarly concentrated in nodular lymphatic cells and was as zirconium uniquely localized in the lysosomes of macrophages where it is associated with phosphorus.