Bayesian spatial modelling of outbreaks of Ebola in Democratic Republic of Congo through the INLA-SPDE approach

2020 
Ebola virus (EBV) disease is globally acknowledged public health emergence, which is endemic in the West and equatorial Africa. To understand the epidemiology especially the dynamic pattern of EBV disease, we analyse the EBV case notification data for confirmed cases and reported deaths of the ongoing outbreak in Democratic Republic of Congo (DRC) between 2018 and 2019, and examined the impart of reported violence of the spread of the virus. Using fully Bayesian geo-statistical analysis through stochastic partial differential equations (SPDE) that allows us to quantify the spatial patterns at every point of the spatial domain. Parameter estimation based on the integrated nested Laplace approximation (INLA). Our findings reveal strong association between violent events in the affected areas and the reported EBV cases and deaths, and the presence of clusters for both cases and deaths both of which spread to neighbouring locations in similar manners. Findings from the study are therefore useful for hotspot identification, location-specific disease surveillance and intervention.
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