Molecular characterization of trophoblast cell surface antigen 2 (Trop-2) positive triple negative breast cancer (TNBC).

Katia Khoury,Rebecca Feldman,Paula R. Pohlmann,Arielle Lutterman Heeke,Zoran Gatalica,Yvonne Veloso,Gregory A. Vidal,Lee S. Schwartzberg,Sandra M. Swain,Claudine Isaacs,Filipa Lynce

Molecular characterization of trophoblast cell surface antigen 2 (Trop-2) positive triple negative breast cancer (TNBC).

2019

Katia Khoury
Rebecca Feldman
Paula R. Pohlmann
Arielle Lutterman Heeke
Zoran Gatalica
Yvonne Veloso
Gregory A. Vidal
Lee S. Schwartzberg
Sandra M. Swain
Claudine Isaacs
Filipa Lynce

e14651Background: Trop-2 is a glycoprotein found in various carcinomas, known to play a role in tumor development and progression. A humanized antibody drug conjugate (ADC) targeting Trop-2 for del...

Keywords:

Cancer research
Antigen
Trophoblast cell
Pathology
Triple-negative breast cancer
Medicine
Glycoprotein
Conjugate
Drug
Humanized antibody

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