Houttuyfonate hybrid and flavonoids preparation and use

The present invention discloses a class of hybrid Houttuyfonate flavonoids preparation method and uses. Said hybrid Houttuyfonate flavonoids, as shown in the structural formula of formula (I): wherein R1 is of formula (II), Formula (III), Formula (IV), Formula (V), Formula (Vl), of formula (VII), formula (VIII), as shown, R2 is formula (IX) or of formula (X) hydrogen, of formula (XI), the formula (XII), the formula (XIII) or formula (XIV) shown in FIG. Genus Houttuynia of the present invention (??. Houttuynia cordata Thunb) from Saururaceae Houttuynia plants were isolated 12 Houttuyfonate hybrid flavonoids, which are novel flavonoid structure furan; using pure vitro a screening system for active herpes virus activity was evaluated, according to the present invention is found Houttuyfonate heteroaryl flavone physical engagement effectively suppress herpes simplex virus, indicates that the present hybrid Houttuyfonate flavonoids has the effect of preventing and treating herpes simplex virus infection, It can be used in the preparation of anti-HSV drugs, with good prospects for research and development.