A phase I study of oxaliplatin (OXA), 5-fluorouracil (5FU) and concomitant preoperative irradiation in patients with locally advanced rectal cancer

3741 Background: OXA could act as a radiosensitizer and has a synergic effect with 5FU, increasing the efficacy of chemoradiotherapy in rectal cancer. This study was performed to determine the viab...