The Endoscopic Treatment of Tracheo-bronchial Amyloidosis: A Challenging Issue

Introduction Localized Tracheo-bronchial Amyloidosis (TBA) represents a rare benign tumor causing irregular and complex airway stenosis due to the deposition of insoluble fibril proteins in airway wall [11. Fiorelli A, Accardo M, Ciancia G, Pettinato G, Santini M (2014) Isolated mediastinal amyloidosis mimicking a neoplastic lesion. Gen Thorac Cardiovasc Surg 62: 324-326.,22. Fiorelli A, Accardo M, Galluccio G, Santini M (2013) Tracheobronchial amyloidosis treated by endobronchial laser resection and self-expanding Y stent. Arch Bronconeumol 49: 303-305.]. Its management may require repeated interventions to treat recurrences and maintain airway patency. We report the clinical course of a patient with symptomatic localized recurrent TBA who was repeatedly treated using different bronchoscopic procedures over a period of three and half years from the first resection.