Complexes of N- and O-Donor Ligands as Potential Urease Inhibitors

Syed Raza Shah,Zarbad Shah,Mohammed Khiat,Ajmal Khan,Leila R. Hill,Shakeel Khan,Javid Hussain,René Csuk,Muhammad U. Anwar,Ahmed Al-Harrasi

Complexes of N- and O-Donor Ligands as Potential Urease Inhibitors

2020

Syed Raza Shah
Zarbad Shah
Mohammed Khiat
Ajmal Khan
Leila R. Hill
Shakeel Khan
Javid Hussain
René Csuk
Muhammad U. Anwar
Ahmed Al-Harrasi

We report five new transition-metal complexes that inhibit the urease enzyme. Barbituric acid (BTA), thiobarbituric acid (TBA), isoniazid (INZ), and nicotinamide (NCA) ligands were employed in comp...

Keywords:

Urease
Barbituric acid
Medicinal chemistry
Enzyme
Ligand
Isoniazid
Thiobarbituric acid
Nicotinamide
Urease Inhibitors
Chemistry
urease enzyme

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