Randomized trial of a home-based exercise intervention for patients with advanced colorectal cancer: Effects on physical functioning and activity levels.

9633 Background: Considerable evidence demonstrates the benefits of exercise for cancer survivors, but few studies focus on those living with advanced disease. We conducted a randomized trial of a home-based exercise intervention for patients with advanced colorectal cancer (CRC), and investigated the effects on physical functioning (primary) and physical activity. Methods: 152 patients with advanced CRC were recruited through the Community Clinical Oncology Program, and were randomized to: 1) a 4 month home-based exercise intervention (EX), or 2) a relaxation control group (R). Both groups received telephone coaching/prompts, instructional materials, and brief coaching and letters from their provider. The EX arm received pedometers and resistance bands. Participants completed self-reports of physical functioning and activity, and performance tasks (2-min step test, 8-ft up and go, arm curl test, 30-sec sit–to-stand test) at baseline and end of study (EOS). Linear mixed model analysis tested intervention ...