An electrophoretic study of glycolytic enzymes in a human population living at high altitude: the Aymara of northern Chile and western Bolivia

An electrophoretic survey of seven glycolytic enzymes and the two carbonic anhydrase isoenzymes in the Aymara of northern Chile and western Bolivia shows no genetically determined structural variation in these enzymes which can be attributed to adaptation to hypoxia. These studies are in agreement with previous studies showing restricted genetic variation in the enzymes of the glycolytic pathway in man.