Saline Infusion Sonohysterography

Saline infusion sonohysterography (SIS) is an invaluable imaging tool for the clinician to assess the uterus, endometrial lining, and endocervical canal. It is useful for evaluating a wide range of pathologies including polyps, leiomyomata, adhesions, anomalies, and endometrial hyperplasia or cancer. SIS is an office procedure that is simple, inexpensive, and low-risk, and it has a sensitivity and specificity that compare favorably with hysterosalpingogram (HSG) or hysteroscopy. When combined with newer modifications such as 3D sonography or tubal patency evaluation, SIS becomes an even more powerful tool. This chapter provides clinically relevant material for the clinician who wishes to develop this skill and includes SIS images of normal and pathologic findings for review.