ASSOCIATION OF HUMANIN A NOVEL MITOCHONDRIAL PROTEIN WITH HUMAN HEART FAILURE: AN ASSESSMENT OF MORTALITY AND CLINICAL BIOMARKERS

Mitochondrial dysfunction has been implicated in the early pathophysiology of heart failure (HF) of varied etiologies. Humanin (HN) is a novel mitochondrial peptide that promotes mitochondrial biogenesis and anti-apoptotic effects. Prior studies suggest that HN is cardioprotective by these