Sap11/Sap12 and egc Associated Toxin Genes are Dominant in Slime Forming Clinical Staphylococcus Aureus Isolates

The prevalence of adhesion (icaA and icaD) and toxin (tst, Staphylococcus aureus isolates. The icaA, icaD, eta, etb and t 1% a comb genes 100 group group gene with 21 ( differ predo isolat cluste the c isolat be att island The d genes . aureus may be under genes coloni comm ﺔﺌﻓ ﻦﻣ قﺎﺼﺘﻟﻻا تﺎﻨﻴﺟ ﺪﻳﺪﺤﺗ ﺔﺳارﺪﻟا ﻩﺬه ﻲﻓ icaA, icaD ﻚﻟﺬآو ، ﺔﻴﺒ هﺬﻟا ﺔﻳدﻮﻘﻨﻌﻟا ﺎﻳﺮﻴﺘﻜﺒﻟا S.aureus تﺎﻨﻴﺟ دﻮﺟو ﻢﺗ ﺪﻗو icaA و ﻰ ا . eta , and etb) genes was studied in 100 clinical st ge nes were detected by PCR in 91%, 91%, 2%, nd 43% of the isolates, respectively. Various gene inations with the previously reported enterotoxin (sea, sec, sei, seg and seh) were detected in 47 of isolates. These combinations fall into 3 groups: I which includes one eta+sea containing isolate, II which includes 25 (53.2%) isolates lacking tst but harboring icaA+icaD genes in 11 combinations the enterotoxin genes and group III which includes 44.7%) isolates harboring icaA+icaD+tst in 7 ent combinations with the enterotoxin genes. The minant gene combinations in group II and III es include seg + sei or seg of the enterotoxin gene r (egc). Furthermore, 20 isolates of group III have orresponding gene combination profiles of 20 es of group II in addition to the tst gene. This could ributed to loss or acquisition of SaPI1 and/or SaPI2 s which carry the tst gene. ominancy of SaPI1/SaPI2 and egc associated toxin in the slimy isolates of S stood in the context of p athogenicity functioning . This data would contribute to the control of zation and spread of these isolates in hospitals and unity at large. تﺎﺌﻓ ﻦﻣ ﺔﻴﻤ ﺴﻟا تﺎﻨﻴﺟ efb و eta