KAAACI Standardization Committee Report on the procedures and applications of the diagnostic tests for drug allergy

Diagnostic methods for drug allergy include the patient’s history, in vivo skin test, in vitro laboratory test, and provocation test. How-ever, the history is often not reliable, procedures for in vivo and in vitro tests are not standardized, and provocation tests are some-times harmful to patients. Generally, skin prick and intradermal tests are useful for immediate reactions; in contrast, patch test and delayed reading of both skin prick and intradermal tests are helpful for delayed reactions. A drug provocation test is the gold stan-dard for both responses, and it is necessary to be aware of exact indications and contraindications with appropriate drugs, doses, and intervals. To date, several methods have been developed to detect culprit agents for drug hypersensitivity reactions, but they are neither completely well validated nor standardized. Based on this awareness and necessity, the Korean Academy of Asthma, Al-lergy and Clinical Immunology launched the Standardization Committee to review the international guidelines and the literature, and then developed the consensus report on the procedures and applications of diagnostic tests for drug allergy. (Allergy Asthma Respir Dis 2017;5:239-247)