Clinical manifestations and misdiagnosis of anaphylactoid purpura abdominalis in adults

2012 
【Objective】To observe the clinical manifestations and misdiagnosis of anaphylactoid purpura abdominalis in adults in order to get better understanding of the disease. 【Methods】102 patients admitted into Xiangya Hospital as anaphylactoid purpura from January 2002 to December 2007, were divided into two groups by abdominal symptoms, the abdominal group and the non-abdominal group. Retrospective analysis was conducted upon clinical manifestations. 【Results】For the abdominal group, main clinical symptoms included skin rash (100%), abdominal pain (100%), gastrointestinal hemorrhage (72.7%), vomit ( 37.9% ) and diarrhea (34.8%). Endoscopy demonstrated the damages to the mucosa fluctuated from congestion, edema, petechia to erosion and multiple ulcers predominantly in the duodenum and the terminal ileum. There was no statistical difference in onset season, upper respiratory infection, onset age, arthralgia and renal involvement, hematuria, proteinuria between two groups. However, patients with abdominal symptoms had higher white blood cell counts, higher serum C -reactive protein and lower albumin levels than the non -abdominal group. 54.5% patients with anaphylactoid purpura abdominalis could be misdiagnosed. 【Conclusions】Patients with anaphylactoid purpura abdominalis may have severe gastrointestinal symptoms,while relatively minor signs. Endoscopy shows the lesions predominantly in the duodenum and terminal ileum. The abdominal group has higher white blood cell counts, higher serum C-reactive protein, but lower albumin levels than the non -abdominal group. Anaphylactoid purpura abdominalis patients, especially those with abdominal symptoms as onset clinical manifestation have a high risk of misdiagnosis.
    • Correction
    • Source
    • Cite
    • Save
    • Machine Reading By IdeaReader
    0
    References
    0
    Citations
    NaN
    KQI
    []