Der Stellenwert von Kombinationsbehandlung in der Versorgung schizophrener Störungen Roland Vauth und Rolf-Dieter Stieglitz

Pharmacological treatment focuses on positive symptoms, cognitive dysfunctioning, negative symptoms and depression in schizophrenia. High level of side effects or low efficacy of antipsychotic treatment causes high risks either for compliance and service engagement or successful social and vocational integration of people with schizophrenia. Consequences are a mostly worse psychosocial outcome and high rates of relapse and rehospitalisation. Cognitive behavioral interventions focus on early treatment of prodromal and early schizophrenia, treatment-refractory psychosis. Synergy aspects between psychopharmacological and psychotherapeutic interven- tions are presented and also risks factors for impeding effects of psychotherapy by a suboptimal pharmacological treatment regime.