Effect of hemodialysis vs peritoneal dialysis on end-stage diabetic nephropathy

Objective To compare the effect of hemodialysis(HD) and peritoneal dialysis(PD) on end-stage diabetic nephropathy patients. Methods A total of 98 patients with end-stage diabetic nephropathy who underwent stable dialysis from June 2013 to June 2016 in our hospital were enrolled in this study, including hemodialysis group with 55 cases and peritoneal dialysis group with 43 cases. There were no significant differences between the two groups on age and gender(P>0.05). The data of all the patients were collected before and 1 year after dialysis. Results There was no significant differences between the two groups in systolic blood pressure, diastolic blood pressure, urine volume, body weight, blood glucose, calcium, phosphorus, potassium, cholesterol, triglyceride, albumin, hemoglobin, urea nitrogen and creatinine before dialysis(P>0.05). One year after dialysis, diastolic blood pressure, blood glucose, calcium, phosphorus, potassium, cholesterol, triglyceride and hemoglobin had no statistical significance between the two groups(P>0.05). While the levels of systolic blood pressure and albumin in the PD group were lower than the HD group (P<0.05) and the levels of urine volume, blood urea nitrogen and creatinine in the PD group were higher than the HD group (P<0.05). The scores of SF-36 and KDTA in the PD group were significantly higher than those in the HD group (P<0.05). Conclusions Both HD and PD are effective in patients with end-stage diabetic nephropathy and both have advantages and disadvantages.Dialysis schemes should be chosen according to concrete condition of the patients. Key words: Hemodialysis; Peritoneal dialysis; End-stage diabetic nephropathy