Knockdown of both p120 catenin and Kaiso promotes expansion of human corneal endothelial monolayers via RhoA-ROCK-noncanonical BMP-NFκB pathway.

Ying-Ting Zhu,Bo Han,Fu Li,Szu-Yu Chen,Sean Tighe,Suzhen Zhang,Scheffer C. G. Tseng

Knockdown of both p120 catenin and Kaiso promotes expansion of human corneal endothelial monolayers via RhoA-ROCK-noncanonical BMP-NFκB pathway.

2014

Ying-Ting Zhu
Bo Han
Fu Li
Szu-Yu Chen
Sean Tighe
Suzhen Zhang
Scheffer C. G. Tseng

Purpose. To determine the signaling pathway involved in expanding contact-inhibited human corneal endothelial cells (HCECs) using p120 and Kaiso small interfering RNAs (siRNAs).

Keywords:

Transcription factor
Bone morphogenetic protein
RHOA
Gene knockdown
Signal transduction
Endothelium
Small interfering RNA
Anatomy
Catenin
Biology
Cell biology
NFKB1
Blot
Phosphorylation
Molecular biology

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