INTRAVENOUS ANTIBACTERIAL USE IN AN UNIVERSITY MEDICAL CENTRE, CAMPO GRANDE, MATO GROSSO DO SUL, BRAZIL Research Article

Many organizations have recommended that antibacterial drug use at national and local levels should be monitored to better understand the relationship between consumption and emerging bacterial resistance. The utilization of scientific methods to evaluate consumption, as Defined Daily Dose (DDD), assists in determining drug use pattern by unit of hospitalization and it has been used to establish the consumption of antibacterial agents. Whereas this therapeutic class is the most used in hospitals, this study aimed to identify the use of standardized and restricted intravenous antibacterial drugs at the University Medical Centre of Federal University of Mato Grosso do Sul during period of November 2007 to April 2008. Data collection was performed using antibacterial request forms and DDD per 100 bed-days. Ceftriaxone was the most requested drug during the study period and its consumption was 6.10 DDD/100 bed-days, followed by ciprofloxacin (4.55 DDD/100 bed-days) and vancomycin (2.15 DDD/100 beddays). The use of DDD methodology enables to visualize the changes that occurred in the antibacterial use pattern, as well as monitoring the consumption of drugs recently included in the therapeutical arsenal.