Cladosporactone A, a unique polyketide with 7-methylisochromen-3-one skeleton from the Deep-Sea-Derived Fungus Cladosporium cladosporioides.

A unique polyketide cladosporactone A ( 1 ), along with eight known compounds ( 2 - 9 ) were isolated from the deep-sea-derived Cladosporium cladosporioides . The structure of 1 was established by spectroscopic analyses, and the absolute configuration was clarified by the theoretical ECD calculation. Compound 1 is the first member of polyketide with 7-methylisochromen-3-one skeleton.