The effects of adaptive support ventilation on respiratory mechanics in elderly patients

Objective To explore the clinical application of adaptive support ventilation (ASV) in elderly patients with acute respiratory failure. Methods A total of 46 mechanically ventilated patients aged over 65 years with acute respiratory failure admitted from January 2013 to June 2015 were enrolled. Comparison between the ASV mode and synchronized intermittent mandatory ventilation (SIMV) mode was carried out in respects of the impacts of both modes on respiratory mechanics, hemodynamics, oxygen availability and comfort rate. Results Difference between ASV and SIMV in respiratory rate was [(20.84±4.04) vs. (24.50±4.60) cycles/min, t=4.04, P 0.05). Conclusions Compared with the synchronized intermittent mandatory ventilation mode, the adaptive support ventilation mode can improve the respiratory mechanics and can increase the comfort rate in the elderly patients with mechanical ventilation. Key words: Elderly; Mechanical ventilation; Adaptive support ventilation; Synchronized intermittent mandatory ventilation; Respiratory mechanics; Hemodynamics; Oxygen dynamics; Comfort degree