1P-239: Synthesis and Functionalization of Gold Nanostars for ROS production

Gold nanoparticles in star shape (called gold nanostars, GNS) were synthesized and coated by N-(3-aminopropyl) methacrylamide hydrochloride (PA) for functionalizing their surface by amine groups and then investigated for reactive oxygen species (ROS) production. The GNS with big size and multi-tips seem to be superior in singlet oxygen production as compared with that of small GNS and less tips. However, the functionalized GNS in small size could also enhance the efficiency of singlet oxygen production about double as compared with that of the intact GNS. In combination with methylene blue (MB+), the functionalized GNS could enhance the singlet oxygen production of MB+ after 1h of LED750 irradiation and no difference between small size and big size on this reaction was observed. In combination with 5-aminolevulinic acid (ALA), only PA-coated GNS could catalyze the oxidation reaction of ALA for singlet oxygen production.