The method that enzymatic high concentration β-aminopropionitrile hydrolysis prepares Beta-alanine

The present invention relates to the methods that enzymatic high concentration β-aminopropionitrile hydrolysis prepares Beta-alanine.More specifically, the present invention provides a kind of using nitrilase and its genetic engineering bacterium or the method for combining aspartate ammonia-lyase and its genetic engineering bacterium that high concentration β-aminopropionitrile is hydrolyzed into Beta-alanine, the Beta-alanine are widely used in the medicine such as synthetic pantothenic acid and calcium pantothenate, carnosine, Sodium Pamidronate, Balsalazide or feed and food additives.This method has the distinguishing features such as concentration of substrate is high, reaction condition is mild, pollution-free and process route is simple.