The construction of realistic 3D hemodynamic models of DeBakey III aortic dissection by using CT images and its application in computational mimic analysis

Objective: To explore a simple and precise methods to establish a virtual 3D model of DeBakey III aortic dissections used for computerized mimic analysis of its hemodynamics. Methods: The computed tomographic angiography (CTA) scanning images of four typical types of DeBakey III aortic dissections were obtained to generate 3-dimentional surface models, based on which the tetrahedral meshes were finally created. The generated models were tested for mesh-independent solutions under preliminary predefined inlet /outlet loads and fluid properties. Results: The four models of DeBakey III aortic dissections contained 1857030, 1820501, 1844181 and 1814914 tetrahedrons, respectively, with the length ranging from 427 to 523 mm. Conclusion: The accuracy of the models is highly consistent with the real anatomy. This can pave the way for the clinical application of computational fluid dynamics simulation in aortic diseases in the future work. (authors)