A Rise in Tonic Luteinizing Hormone Secretion Occurs during Photoperiod-Stimulated Sexual Maturation of the Female Ferret*

This study determined whether a rise in tonic secretion of LH occurred before long day-induced precocious puberty of the female ferret. Twenty immature females were assigned to 1 of 2 photoperiods at 15 weeks of age. Ten ferrets were placed in a long day, stimulatory photoperiod (16 h of light, 8 h of darkness) to induce sexual maturation, and 10 remained in the nonstimulatory photoperiod (8 h of light, 16 h of darkness) for the duration of the study. Intensive blood sampling regimens (every 10 min for 8 h) were conducted at selected times after the onset of long days to permit definition of detailed secretory patterns of plasma LH. Females in each photoperiod were sampled from chronic jugular venous catheters approximately twice weekly until puberty was evident in females housed in long days. The end point for determination of the pubertal onset of adult ovarian function was the appearance of estrogen-sensitive vulvar edema. Results show a marked increase in frequency of episodes of LH secretion per 8-h ...