Polycomb group-dependent imprinting of the actin regulator AtFH5 regulates morphogenesis in Arabidopsis thaliana
2009
During embryogenesis, Polycomb group (PcG) complexes deposit silencing
histone modifications and target homeotic genes, which regulate the patterning
of other transcription factors. This transcriptional network further maintains
cell fate. However, genome-wide identification of histone modifications has
suggested that PcG complexes might regulate genes other than those encoding
transcription factors. In Arabidopsis , we show that PcG activity
directly targets the actin regulator formin ARABIDOPSIS FORMIN HOMOLOGUE
5 ( AtFH5 ). PcG activity silences the paternal allele of
AtFH5 , restricting its expression to the maternal allele.
AtFH5 thus appears to be a new, maternally expressed imprinted gene.
We further demonstrate that AtFH5 is responsible for morphological
defects caused by the loss of PcG activity in the seed.
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