Scanning electron microscopic observations of the pathomorphology of the distal airways and alveolar region in the goat

1997 
Abstract Four goats with respiratory disorders were examined in the present study, two were diagnosed during routine ante-mortem inspection, one at post-mortem (PM) and the other was referred in the department. Samples were taken from the lung parenchyma to include bronchioles (small and terminal), respiratory bronchioles, alveolar ducts and alveolar membrane. Samples were routinely prepared for light microscopy (LM) and scanning electron microscopy (SEM). Changes revealed by SEM included: poor ciliation of the bronchioles, luminal surfaces of the alveoli being covered by secretions in the form of amorphous sheets, engorged blood capillaries, accumulation of flocculent materials in the lumina of bronchioles and respiratory bronchioles and the increase in the number of Type II pneumocytes, in addition to the collapse of apical protuberances of the nonciliated bronchiolar epithelial cells. A thorough discussion of these changes is provided. It is concluded that SEM can reveal changes that could not be determined by other conventional methods although it can not replace them.
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