Feocromocitoma y Paraganglioma: Más allá de la clínica

Pheochromocytomas and Paragangliomas are rare tumors, originated from chromaffin cells. Those have a broad clinical spectrum from incidental finding to full clinical manifestations explain to overproduction of catecholamines. The biochemistry diagnosis is made by the measurement of free metanephrines in plasma or fractioned metanephrines in urine. Complete surgical removal is the optimal treatment, before α y β blockage. In case of metastasic disease treatment options are limited with a low rate response; the use of immunotherapy is under investigation.